[HTML][HTML] Macrolide Resistance in Treponema pallidum in the United States and Ireland

SA Lukehart, C Godornes, BJ Molini… - … England Journal of …, 2004 - Mass Medical Soc
SA Lukehart, C Godornes, BJ Molini, P Sonnett, S Hopkins, F Mulcahy, J Engelman…
New England Journal of Medicine, 2004Mass Medical Soc
An HIV-infected patient in San Francisco with primary syphilis was treated with azithromycin,
but the lesion did not resolve. The authors of this case report confirmed resistance to
azithromycin and identified a mutation in the 23S rRNA genes of T. pallidum. The mutation
was also found in samples collected in Baltimore, Seattle, and Dublin.
An HIV-infected patient in San Francisco with primary syphilis was treated with azithromycin, but the lesion did not resolve. The authors of this case report confirmed resistance to azithromycin and identified a mutation in the 23S rRNA genes of T. pallidum. The mutation was also found in samples collected in Baltimore, Seattle, and Dublin.
The New England Journal Of Medicine