Respiratory virus infection of mice provokes a permanent humoral immune response

L Hyland, M Sangster, R Sealy, C Coleclough - Journal of virology, 1994 - Am Soc Microbiol
L Hyland, M Sangster, R Sealy, C Coleclough
Journal of virology, 1994Am Soc Microbiol
We have observed that respiratory virus infection of mice provokes an extremely persistent
humoral immune reaction, due to a long-sustained population of antibody-secreting cells in
the bone marrow. Theories of humoral immunity that strongly distinguish primary and
secondary reactions thus may not adequately describe the immune response to respiratory
viruses.
We have observed that respiratory virus infection of mice provokes an extremely persistent humoral immune reaction, due to a long-sustained population of antibody-secreting cells in the bone marrow. Theories of humoral immunity that strongly distinguish primary and secondary reactions thus may not adequately describe the immune response to respiratory viruses.
American Society for Microbiology