[HTML][HTML] MicroRNA expression signature and the role of microRNA-21 in the early phase of acute myocardial infarction
S Dong, Y Cheng, J Yang, J Li, X Liu, X Wang… - Journal of Biological …, 2009 - ASBMB
Several recent reports have suggested that microRNAs (miRNAs) might play critical roles in
acute myocardial infarction (AMI). However, the miRNA expression signature in the early
phase of AMI has not been identified. In this study, the miRNA expression signature was
investigated in rat hearts 6 h after AMI. Compared with the expression signature in the
noninfarcted areas, 38 miRNAs were differentially expressed in infarcted areas and 33
miRNAs were aberrantly expressed in the border areas. Remarkably, miR-21 expression …
acute myocardial infarction (AMI). However, the miRNA expression signature in the early
phase of AMI has not been identified. In this study, the miRNA expression signature was
investigated in rat hearts 6 h after AMI. Compared with the expression signature in the
noninfarcted areas, 38 miRNAs were differentially expressed in infarcted areas and 33
miRNAs were aberrantly expressed in the border areas. Remarkably, miR-21 expression …