Congenital neutropenia syndromes comprise a heterogeneous group of inherited disorders.
Hereditary conditions associated with low neutrophil counts are persistent and need to be
differentiated from neutropenia secondary to autoimmune processes or other pathologic
conditions, such as myelodysplasia or leukemia. Clinically, congenital neutropenia is
characterized by recurrent bacterial infections. Recently, several novel genetic defects were
described in patients with congenital neutropenia, shedding light on the pathophysiology of …