Rapid effect of inhaled ciclesonide in asthma: a randomized, placebo-controlled study
EM Erin, AS Zacharasiewicz, GC Nicholson, AJ Tan… - Chest, 2008 - Elsevier
Background Ciclesonide is a novel inhaled corticosteroid for the treatment of asthma, and it
is important to measure the onset of effect of this therapy on airway hyperresponsiveness
(AHR), exhaled nitric oxide (NO), and levels of eosinophils in induced sputum. Methods In a
randomized, double-blind, crossover study, 21 patients with mild asthma inhaled ciclesonide
320 μg (ex-actuator) qd, ciclesonide 640 μg (ex-actuator) bid, and placebo for 7 days.
Exhaled NO and AHR to adenosine monophosphate (AMP), measured as the provocative …
is important to measure the onset of effect of this therapy on airway hyperresponsiveness
(AHR), exhaled nitric oxide (NO), and levels of eosinophils in induced sputum. Methods In a
randomized, double-blind, crossover study, 21 patients with mild asthma inhaled ciclesonide
320 μg (ex-actuator) qd, ciclesonide 640 μg (ex-actuator) bid, and placebo for 7 days.
Exhaled NO and AHR to adenosine monophosphate (AMP), measured as the provocative …
