Muscle satellite cells are believed to represent a committed stem cell population that is
responsible for the postnatal growth and regeneration of skeletal muscle. However, the
observation that cultured myoblasts differentiate into osteocytes or adipocytes following
treatment with bone morphogenetic proteins (BMPs) or adipogenic inducers, respectively,
suggests some degree of plasticity within the mesenchymal lineage. To further investigate
this phenomenon, we explore the osteogenic and adipogenic potential of satellite cells …