[HTML][HTML] Adiposity elevates plasma MCP-1 levels leading to the increased CD11b-positive monocytes in mice
K Takahashi, S Mizuarai, H Araki, S Mashiko… - Journal of Biological …, 2003 - ASBMB
Obesity is currently considered as an epidemic in the western world, and it represents a
major risk factor for life-threatening diseases such as heart attack, stroke, diabetes, and
cancer. Taking advantage of DNA microarray technology, we tried to identify the molecules
explaining the relationship between obesity and vascular disorders, comparing mRNA
expression of about 12,000 genes in white adipose tissue between normal, high fat diet-
induced obesity (DIO) and d-Trp 34 neuropeptide Y-induced obesity in mice. Expression of …
major risk factor for life-threatening diseases such as heart attack, stroke, diabetes, and
cancer. Taking advantage of DNA microarray technology, we tried to identify the molecules
explaining the relationship between obesity and vascular disorders, comparing mRNA
expression of about 12,000 genes in white adipose tissue between normal, high fat diet-
induced obesity (DIO) and d-Trp 34 neuropeptide Y-induced obesity in mice. Expression of …