[HTML][HTML] The fission yeast copper-sensing transcription factor Cuf1 regulates the copper transporter gene expression through an Ace1/Amt1-like recognition sequence
J Beaudoin, S Labbé - Journal of Biological Chemistry, 2001 - ASBMB
Transcriptional regulation of genes encoding critical components of copper transport is
essential for copper homeostasis and growth in yeast. Analysis of regulatory regions in the
promoter of the ctr4+ copper transporter gene in fission yeast Schizosaccharomyces pombe
reveals the identity of a conserved copper-signalingelement (CuSE), which is recognized by
the transcription factor Cuf1. We demonstrate that CuSE is necessary for transcriptional
activation in response to copper deprivation conditions. Interestingly, the CuSE element …
essential for copper homeostasis and growth in yeast. Analysis of regulatory regions in the
promoter of the ctr4+ copper transporter gene in fission yeast Schizosaccharomyces pombe
reveals the identity of a conserved copper-signalingelement (CuSE), which is recognized by
the transcription factor Cuf1. We demonstrate that CuSE is necessary for transcriptional
activation in response to copper deprivation conditions. Interestingly, the CuSE element …