Absence of subcommissural organ in the cerebral aqueduct of congenital hydrocephalus spontaneously occurring in MT/HokIdr mice

IK Takeuchi, R Kimura, M Matsuda, R Shoji - Acta neuropathologica, 1987 - Springer
IK Takeuchi, R Kimura, M Matsuda, R Shoji
Acta neuropathologica, 1987Springer
The midbrains of pups with congenital hydrocephalus spontaneously occurring in MT/HokIdr
mice were histologically examined. The subcommissural organ (SCO) and the posterior
commissure were completely absent in the hydrocephalic brain. The cerebral aqueduct in
the hydrocephalic brain was never completely stenosed, though it was somewhat narrowed
in its middle region as compared with that in the normal brain. a possible interrelationship
between an absence of SCO and a cause of congenital hydrocephalus is discussed.
Summary
The midbrains of pups with congenital hydrocephalus spontaneously occurring in MT/HokIdr mice were histologically examined. The subcommissural organ (SCO) and the posterior commissure were completely absent in the hydrocephalic brain. The cerebral aqueduct in the hydrocephalic brain was never completely stenosed, though it was somewhat narrowed in its middle region as compared with that in the normal brain. a possible interrelationship between an absence of SCO and a cause of congenital hydrocephalus is discussed.
Springer