A review of Epstein-Barr virus infection in patients with immunodeficiency disorders

M Okano, TG Gross - The American journal of the medical sciences, 2000 - Elsevier
ABSTRACT Epstein-Barr virus (EBV), one of 8 known human herpesviruses, infects the vast
majority of mankind and infections are generally subclinical. However, EBV infection has
been associated with a spectrum of diseases, Iymphoproliferative diseases (EBV-LPD) in
particular, including malignant lymphoma. EBV-LPD are frequently observed in patients with
primary or secondary immunodeficiencies. The incidence of EBV-LPD is on the rise, partly
because of increasing numbers and success of hematopoietic stem cell and solid organ …