The complement system in bullous pemphigoid. III. Fixation of C1q and C4 by pemphigoid antibody
RE Jordon, JM Nordby… - The Journal of Laboratory …, 1975 - translationalres.com
By in vitro complement immunofluorescent staining methods, 46 serum samples from
bullous pemphigoid patients with titers of antibasement-membrane-zone antibodies of 320
or greater were tested for their ability to fix C1q, C4, and C3. All three staining reactions were
positive with 23 of the samples; 21 samples yielded negative reactions. With one sample,
the C1q and C3 staining reactions were positive but the C4 reaction was negative; one other
sample gave a positive C3 staining reaction only. Absorption of anti-C1q, anti-C4, and anti …
bullous pemphigoid patients with titers of antibasement-membrane-zone antibodies of 320
or greater were tested for their ability to fix C1q, C4, and C3. All three staining reactions were
positive with 23 of the samples; 21 samples yielded negative reactions. With one sample,
the C1q and C3 staining reactions were positive but the C4 reaction was negative; one other
sample gave a positive C3 staining reaction only. Absorption of anti-C1q, anti-C4, and anti …