Molecular mechanisms of diverse actions of prostanoid receptors
M Negishi, Y Sugimoto, A Ichikawa - … et Biophysica Acta (BBA)-Lipids and …, 1995 - Elsevier
Prostanoids comprise prostaglandins (PGs) and thromboxanes (TXs), are synthesized via
tbe cyclooxygenase pathway from arachidonic acid by a variety of cells in response to
various physiological or pathological stimuli [1]. They are then quickly released outside of
the cells and act as local hormones in the vicinity of their production site to maintain local
homeostasis. They exert a wide spectrum of actions in the body, which are mediated by
specific receptors on plasma membranes. Prostanoid receptors have been first …
tbe cyclooxygenase pathway from arachidonic acid by a variety of cells in response to
various physiological or pathological stimuli [1]. They are then quickly released outside of
the cells and act as local hormones in the vicinity of their production site to maintain local
homeostasis. They exert a wide spectrum of actions in the body, which are mediated by
specific receptors on plasma membranes. Prostanoid receptors have been first …