Effect of surface active lipoprotein on clotting and fibrinolysis, and of fibrinogen on surface tension of surface active lipoprotein: with a hypothesis on the pathogenesis …
FB Taylor Jr, ME Abrams - The American Journal of Medicine, 1966 - Elsevier
We studied the effect of a surface active lipoprotein extracted from the lungs of rabbits, lambs
and man on the coagulation and fibrinolytic enzyme systems in the lungs. The lipoprotein
accelerated generation of thromboplastin and inhibited activation of the fibrinolytic enzyme
system. Conversely, fibrinogen inhibited surface activity of the lipoprotein in molar ratios
(fibrinogen: lipoprotein) of 1: 1 and higher. Albumin, gamma globulin, plasminogen and
plasmin failed to reduce the surface activity of the lipoprotein; 6 M urea partially restored the …
and man on the coagulation and fibrinolytic enzyme systems in the lungs. The lipoprotein
accelerated generation of thromboplastin and inhibited activation of the fibrinolytic enzyme
system. Conversely, fibrinogen inhibited surface activity of the lipoprotein in molar ratios
(fibrinogen: lipoprotein) of 1: 1 and higher. Albumin, gamma globulin, plasminogen and
plasmin failed to reduce the surface activity of the lipoprotein; 6 M urea partially restored the …