Possible role of the 4G/5G polymorphism of the plasminogen activator inhibitor 1 gene in the development of asthma
RESULTS The distribution of the genotypes in the 102 children with asthma was determined
as follows: 43 (42.2%) with* 4G/4G, 50 (49.1%) with* 4G/5G, and 9 (8.8%) with* 5G/5G. The
prevalence of the* 4G allele was higher in this population than that in the normal
populations of previous reports. 2 The results of the TDT between the* 4G and* 5G alleles in
asthma and atopy in the families are shown in Table I. The* 4G allele was preferentially
transmitted to asthma-affected children (χ2= 6.6, P=. 0139). However, there was a lack of …
as follows: 43 (42.2%) with* 4G/4G, 50 (49.1%) with* 4G/5G, and 9 (8.8%) with* 5G/5G. The
prevalence of the* 4G allele was higher in this population than that in the normal
populations of previous reports. 2 The results of the TDT between the* 4G and* 5G alleles in
asthma and atopy in the families are shown in Table I. The* 4G allele was preferentially
transmitted to asthma-affected children (χ2= 6.6, P=. 0139). However, there was a lack of …