Comparison of protein synthesis and degradation in incubated and perfused muscle.
AS Clark, WE Mitch - Biochemical Journal, 1983 - ncbi.nlm.nih.gov
AS Clark, WE Mitch
Biochemical Journal, 1983•ncbi.nlm.nih.govRates of muscle protein synthesis and degradation measured in the perfused hindquarter
were compared with those in incubated epitrochlearis muscles. With fed or starved mature
rats, results without insulin treatment were identical. With insulin treatment, protein synthesis
in perfused hindquarters was greater, though protein degradation was the same. Thus rates
of muscle protein degradation estimated by these two methods in vitro correspond closely.
were compared with those in incubated epitrochlearis muscles. With fed or starved mature
rats, results without insulin treatment were identical. With insulin treatment, protein synthesis
in perfused hindquarters was greater, though protein degradation was the same. Thus rates
of muscle protein degradation estimated by these two methods in vitro correspond closely.
Abstract
Rates of muscle protein synthesis and degradation measured in the perfused hindquarter were compared with those in incubated epitrochlearis muscles. With fed or starved mature rats, results without insulin treatment were identical. With insulin treatment, protein synthesis in perfused hindquarters was greater, though protein degradation was the same. Thus rates of muscle protein degradation estimated by these two methods in vitro correspond closely.
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