Estimates of the number of loci contributing to the histoincompatibility between C57BL/6 and BALB/c strains of mice

DW BAILEY, LE MOBRAATEN - Transplantation, 1969 - journals.lww.com
DW BAILEY, LE MOBRAATEN
Transplantation, 1969journals.lww.com
The number of histocompatibility loci at which the inbred mouse strains, C57BL/6By and
BALB/cBy, differ was estimated in three independent experiments. The first experiment was
based on survival of parental inbred strain grafts on F 2 hosts and provided an estimate of at
least 17 loci; the second was based on survival of grafts exchanged between sibs of partially
inbred lines and provided an estimate of 28 loci; and the third was based on survival of skin
from fifth generation backcross mice grafted on parental strain hosts and provided an …
Abstract
The number of histocompatibility loci at which the inbred mouse strains, C57BL/6By and BALB/cBy, differ was estimated in three independent experiments. The first experiment was based on survival of parental inbred strain grafts on F 2 hosts and provided an estimate of at least 17 loci; the second was based on survival of grafts exchanged between sibs of partially inbred lines and provided an estimate of 28 loci; and the third was based on survival of skin from fifth generation backcross mice grafted on parental strain hosts and provided an estimate of 29 loci.
Lippincott Williams & Wilkins