Pathology of growth hormone-producing tumors of the human pituitary.
K Kovacs, E Horvath - Seminars in Diagnostic Pathology, 1986 - europepmc.org
K Kovacs, E Horvath
Seminars in Diagnostic Pathology, 1986•europepmc.orgThis paper reviews the morphologic features of growth hormone-producing tumors of the
human pituitary. These tumors are associated with elevated blood growth hormone levels
and acromegaly or gigantism and can be classified into the following morphologically
distinct entities by the combined application of histology, immunocytology, and electron
microscopy: densely granulated growth hormone cell adenoma; sparsely granulated growth
hormone cell adenoma; mixed growth hormone cell-prolactin cell-adenoma; acidophil stem …
human pituitary. These tumors are associated with elevated blood growth hormone levels
and acromegaly or gigantism and can be classified into the following morphologically
distinct entities by the combined application of histology, immunocytology, and electron
microscopy: densely granulated growth hormone cell adenoma; sparsely granulated growth
hormone cell adenoma; mixed growth hormone cell-prolactin cell-adenoma; acidophil stem …
This paper reviews the morphologic features of growth hormone-producing tumors of the human pituitary. These tumors are associated with elevated blood growth hormone levels and acromegaly or gigantism and can be classified into the following morphologically distinct entities by the combined application of histology, immunocytology, and electron microscopy: densely granulated growth hormone cell adenoma; sparsely granulated growth hormone cell adenoma; mixed growth hormone cell-prolactin cell-adenoma; acidophil stem cell adenoma; mammosomatotroph cell adenoma; growth hormone cell carcinoma; plurihormonal adenoma with growth hormone production.
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