Publisher Summary Preparation of brain mitochondria that are metabolically active and, at
the same time, free from nonmitochondrial contaminants, has been a recognized problem.
The difficulties encountered in preparing brain mitochondrial populations that fulfill both
criteria are inherent in the fact that nervous tissue not only is very heterogeneous but also
contains large amounts of lipid and membranous materials. The metabolism of a variety of
substances, such as the citric acid cycle intermediates and neurotransmitters, such as …