Multiple-organ failure: generalized autodestructive inflammation?

RJA Goris, TPA te Boekhorst, JKS Nuytinck… - Archives of …, 1985 - jamanetwork.com
• As multiple-organ failure (MOF) has been generally associated with sepsis, the importance
of bacterial sepsis was evaluated retrospectively in 55 trauma and 37 intra-abdominal—
sepsis patients with MOF. The severity of MOF was graded, and an analysis was made of
day of onset, incidence, severity, sequence, and mortality of organ failures. No difference
was found between groups in sequence, severity, or mortality of organ failures. In contrast,
bacterial sepsis was found in 65% of intra-abdominal—sepsis patients but only in 33% of …