Sepsis syndrome: a valid clinical entity

RC BONE, JR CHARLES J FISHER… - Critical care …, 1989 - journals.lww.com
The sepsis syndrome represents a systemic response to infection and is defined as
hypothermia (temperature< 96 0 F) or hypothermia (> 101 0 F), tachycardia (> 90 beat/min),
tachypnea (> 20 breath/min), clinical evidence of an infection site and with at least one end-
organ demonstrating inadequate perfusion or dysfunction expressed as poor or altered
cerebral function, hypoxemia (Pao 2< 75 torr), elevated plasma lactate, or oliguria (urine
output< 30 ml/h or 0.5 ml/kg body weight. h without corrective therapy). One hundred ninety …