Overexpression of Bcl-2 in the intestinal epithelium improves survival in septic mice
CM Coopersmith, KC Chang, PE Swanson… - Critical care …, 2002 - journals.lww.com
Objectives The aim of this study was to determine whether decreasing intestinal epithelial
apoptosis in sepsis would alter mortality rates. The roles of the antiapoptotic protein Bcl-2
and the “executioner” protease caspase-3 in sepsis-induced gut cell death also were
evaluated. Design
apoptosis in sepsis would alter mortality rates. The roles of the antiapoptotic protein Bcl-2
and the “executioner” protease caspase-3 in sepsis-induced gut cell death also were
evaluated. Design