[HTML][HTML] Co-expression of VEGF-C and its receptors, VEGFR-2 and VEGFR-3, in endothelial cells of lymphangioma. Implication in autocrine or paracrine regulation of …

HY Huang, CC Ho, PH Huang, SM Hsu - Laboratory investigation, 2001 - Elsevier
Lymphangioma has long been thought of as congenital malformations resulting from the
failure of lymphatic vessels communicating with the venous system in the fetal period.
Alternatively, it is proposed to be true neoplasm originated from the transformation of
lymphatic endothelia. To extend the molecular basis of the pathogenesis of lymphangioma,
we have characterized the expression of vascular endothelial growth factor (VEGF) and
VEGF receptors (VEGFR) in 29 cases of lymphangioma by RNA in situ hybridization …