Noninvasive Study of High-Energy Phosphate Metabolism in Human Heart by Depth-Resolved 31P NMR Spectroscopy
PA Bottomley - Science, 1985 - science.org
Science, 1985•science.org
Phosphorus-31 nuclear magnetic resonance (NMR) spectra showing the relative
concentrations of high-energy phosphate metabolites have been recorded noninvasively
from the human heart in vivo. Spectral data were spatially localized by combining a pulsed
magnetic field gradient with surface NMR excitation-detection coils. The location of the
selected spectral region was determined by conventional proton NMR imaging immediately
before examination by phosphorus-31 NMR spectroscopy.
concentrations of high-energy phosphate metabolites have been recorded noninvasively
from the human heart in vivo. Spectral data were spatially localized by combining a pulsed
magnetic field gradient with surface NMR excitation-detection coils. The location of the
selected spectral region was determined by conventional proton NMR imaging immediately
before examination by phosphorus-31 NMR spectroscopy.
Phosphorus-31 nuclear magnetic resonance (NMR) spectra showing the relative concentrations of high-energy phosphate metabolites have been recorded noninvasively from the human heart in vivo. Spectral data were spatially localized by combining a pulsed magnetic field gradient with surface NMR excitation-detection coils. The location of the selected spectral region was determined by conventional proton NMR imaging immediately before examination by phosphorus-31 NMR spectroscopy.
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