Characterization of human homologue of 4-1BB and its ligand
Z Zhou, S Kim, J Hurtado, ZH Lee, KK Kim, KE Pollok… - Immunology letters, 1995 - Elsevier
The human homologue of 4-1BB (H4-1BB) cDNA was isolated from PMA plus ionomycin-
treated human peripheral T-cell cDNA libraries. The amino acid sequence deduced from the
nucleotide sequence showed that the protein is composed of 255 amino acids with 2
potential N-linked glycosylation sites. The molecular weight of its protein backbone is
calculated to be 27 kDa. The H4-1BB contains features such as signal sequence and
transmembrane domain, indicating that it is a receptor protein. This protein showed 60 …
treated human peripheral T-cell cDNA libraries. The amino acid sequence deduced from the
nucleotide sequence showed that the protein is composed of 255 amino acids with 2
potential N-linked glycosylation sites. The molecular weight of its protein backbone is
calculated to be 27 kDa. The H4-1BB contains features such as signal sequence and
transmembrane domain, indicating that it is a receptor protein. This protein showed 60 …