Opioid peptides modulate production of interferon γ by human mononuclear cells
SL Brown, DE Van Epps - Cellular immunology, 1986 - Elsevier
The opioid neuropeptides have previously been shown to bind to and affect leukocyte
function including lymphocyte proliferation, NK-cell activity, mononuclear cell chemotaxis,
immunoglobulin synthesis, and lymphokine production. The effect of the opioid peptides β-
endorphin and Met-enkephalin on interferon γ (IFN) production by concanavalin A-
stimulated human mononuclear cells was examined. Both β-endorphin and Met-enkephalin
enhanced IFN production by the majority of donor mononuclear cells tested and did so at …
function including lymphocyte proliferation, NK-cell activity, mononuclear cell chemotaxis,
immunoglobulin synthesis, and lymphokine production. The effect of the opioid peptides β-
endorphin and Met-enkephalin on interferon γ (IFN) production by concanavalin A-
stimulated human mononuclear cells was examined. Both β-endorphin and Met-enkephalin
enhanced IFN production by the majority of donor mononuclear cells tested and did so at …