[HTML][HTML] Binding specificity for RACK1 resides in the V5 region of βII protein kinase C
EG Stebbins, D Mochly-Rosen - Journal of Biological Chemistry, 2001 - ASBMB
Identification of selective anchoring proteins responsible for specialized localization of
specific signaling proteins has led to the identification of new inhibitors of signal
transduction, inhibitors of anchoring protein-ligand interactions. RACK1, the firstreceptor for
activated C kinase identified in our lab, is a selective anchoring protein for βII protein kinase
C (βIIPKC). We previously found that at least part of the RACK1-binding site resides in the
C2 domain of βIIPKC (Ron, D., Luo, J., and Mochly-Rosen, D.(1995) J. Biol. Chem. 270 …
specific signaling proteins has led to the identification of new inhibitors of signal
transduction, inhibitors of anchoring protein-ligand interactions. RACK1, the firstreceptor for
activated C kinase identified in our lab, is a selective anchoring protein for βII protein kinase
C (βIIPKC). We previously found that at least part of the RACK1-binding site resides in the
C2 domain of βIIPKC (Ron, D., Luo, J., and Mochly-Rosen, D.(1995) J. Biol. Chem. 270 …
