Exercise induces recruitment of the “insulin-responsive glucose transporter”. Evidence for distinct intracellular insulin-and exercise-recruitable transporter pools in …
AG Douen, T Ramlal, S Rastogi, PJ Bilan… - Journal of Biological …, 1990 - ASBMB
Acute exercise, like insulin, increases D-glucose uptake into rat hind limb muscles. Here we
examine the distribution of the muscle glucose transporters GLUT-4 and GLUT-1 in plasma
membrane and intracellular membrane fractions of skeletal muscle prepared from control,
exercised, and acutely insulin-treated rats. Immunoblotting with an anti-GLUT-4 polyclonal
antibody showed that acute insulin treatment (by hind limb perfusion or in vivo injection)
increased GLUT-4 transporters in a plasma membrane fraction and decreased them in an …
examine the distribution of the muscle glucose transporters GLUT-4 and GLUT-1 in plasma
membrane and intracellular membrane fractions of skeletal muscle prepared from control,
exercised, and acutely insulin-treated rats. Immunoblotting with an anti-GLUT-4 polyclonal
antibody showed that acute insulin treatment (by hind limb perfusion or in vivo injection)
increased GLUT-4 transporters in a plasma membrane fraction and decreased them in an …