In vivo protein transduction: intracellular delivery of biologically active proteins, compounds and DNA

SR Schwarze, SF Dowdy - Trends in Pharmacological Sciences, 2000 - cell.com
SR Schwarze, SF Dowdy
Trends in Pharmacological Sciences, 2000cell.com
Treatment of cells with drugs that impair cellular transport processes such as brefeldin A, an
inhibitor of golgi transport, does not inhibit transduction5. Thus, the mechanism of protein
transduction remains a difficult question to address experimentally. However, the
identification of specific drugs, if any exist, that inhibit this novel process would be beneficial.
Treatment of cells with drugs that impair cellular transport processes such as brefeldin A, an inhibitor of golgi transport, does not inhibit transduction5. Thus, the mechanism of protein transduction remains a difficult question to address experimentally. However, the identification of specific drugs, if any exist, that inhibit this novel process would be beneficial.
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