[HTML][HTML] Adipose tissue and adipokines—energy regulation from the human perspective

P Trayhurn, C Bing, IS Wood - The Journal of nutrition, 2006 - Elsevier
There has been a rapid rise in the incidence of obesity, primarily as a result of changes in
lifestyle (diet and activity levels). Obesity has provided considerable impetus for the
investigation of the fundamental mechanisms involved in the regulation of energy balance.
Important developments include the identification of novel factors involved in the control of
appetite, such as ghrelin, orexin A, and the endogenous cannabinoids, and the emergence
of the concept of “nonexercise activity thermogenesis”(NEAT) provided new perspectives on …