Epitope-Analyzer: A structure-based webtool to analyze broadly neutralizing epitopes

D Montiel-Garcia, O Rojas-Labra… - Journal of Structural …, 2022 - Elsevier
The antigenic epitope regions of pathogens (eg, viruses) are recognized by antibodies (Abs)
and subsequently cleared by the host immune system, thereby protecting us from disease.
Some of these epitopes are conserved among different variants or subgroups of pathogens
(eg, Influenza (FLU) viruses, Coronaviruses), hence can be targeted for potential broad-
neutralization. Here we report a web-based tool, Epitope Analyzer (EA), that rapidly
identifies conformational epitope and paratope residues in an antigen–antibody complex …