Atopic dermatitis: a genetic-epidemiologic study in a population-based twin sample
FS Larsen, NV Holm, K Henningsen - Journal of the American Academy of …, 1986 - Elsevier
Atopic dermatitis is a multifactorial disease that seems both to rise in frequency and to be
dependent on a genetic predisposition. In order to clarify these issues we encircled a
representative twin series with atopic dermatitis from a total twin population of 592 like-
sexed twin pairs. We found (1) that the cumulative incidence rate (0-7 years) of atopic
dermatitis in Denmark has increased significantly from 0.03 for the birth cohort 1960-1964 to
0.10 for the birth cohort 1970-1974,(2) that monozygotic twin pairs are more often …
dependent on a genetic predisposition. In order to clarify these issues we encircled a
representative twin series with atopic dermatitis from a total twin population of 592 like-
sexed twin pairs. We found (1) that the cumulative incidence rate (0-7 years) of atopic
dermatitis in Denmark has increased significantly from 0.03 for the birth cohort 1960-1964 to
0.10 for the birth cohort 1970-1974,(2) that monozygotic twin pairs are more often …
