[HTML][HTML] The adipose organ of obesity-prone C57BL/6J mice is composed of mixed white and brown adipocytes

A Vitali, I Murano, MC Zingaretti, A Frontini… - Journal of lipid …, 2012 - ASBMB
White and brown adipocytes are believed to occupy different sites in the body. We studied
the anatomical features and quantitative histology of the fat depots in obesity and type 2
diabetes-prone C57BL/6J mice acclimated to warm or cold temperatures. Most of the fat
tissue was contained in depots with discrete anatomical features, and most depots
contained both white and brown adipocytes. Quantitative analysis showed that cold
acclimation induced an increase in brown adipocytes and an almost equal reduction in …