Prostate cancer (PCA) is one of the most prevalent cancers and a major leading cause of
morbidity and mortality in the Western world. The TMPRSS2-ERG fusion was recently
identified as a common recurrent chromosomal aberration in this malignancy. In our study,
we interrogated a broad spectrum of benign, precursor, and malignant prostatic lesions to
assess the TMPRSS2-ERG fusion status using a multicolor interphase fluorescence in situ
hybridization assay. Samples from hospital-based cohorts consisted of 237 clinically …