Inflammation of the airways and lung parenchyma in COPD: role of T cells
MG Cosio, J Majo, MG Cosio - Chest, 2002 - Elsevier
A smoking-induced inflammatory reaction in the airways and lung parenchyma, comprised
mainly of neutrophils and alveolar macrophages, has long been accepted to be the major
cause of COPD in smokers. Recent reports have underlined the role of the T lymphocyte as
a potentially important factor in the inflammatory process leading to COPD. It has been found
that, in the airways and the lung parenchyma, the presence of T cells, predominantly CD8+ T
cells, can distinguish between smokers with and without COPD. In addition to T cells, other …
mainly of neutrophils and alveolar macrophages, has long been accepted to be the major
cause of COPD in smokers. Recent reports have underlined the role of the T lymphocyte as
a potentially important factor in the inflammatory process leading to COPD. It has been found
that, in the airways and the lung parenchyma, the presence of T cells, predominantly CD8+ T
cells, can distinguish between smokers with and without COPD. In addition to T cells, other …