[HTML][HTML] Antiapoptotic protein Bcl-xL is up-regulated during megakaryocytic differentiation of CD34+ progenitors but is absent from senescent megakaryocytes
C Sanz, I Benet, C Richard, B Badia, EJ Andreu… - Experimental …, 2001 - Elsevier
OBJECTIVE: The expression of Bcl-xL has been shown to be regulated during the
maturation process of different hematopoietic cell lineages (ie, erythroid cells, neutrophils,
monocytes/macrophages). In the present study, we examined the expression of Bcl-xL in
megakaryocytes derived from CD34+ progenitors and in the megakaryoblastic cell line UT7.
MATERIALS AND METHODS: Expression of Bcl-xL was analyzed in CD41+ cells cultured in
the presence of thrombopoietin and in UT7 cells treated with phorbol diester by Western …
maturation process of different hematopoietic cell lineages (ie, erythroid cells, neutrophils,
monocytes/macrophages). In the present study, we examined the expression of Bcl-xL in
megakaryocytes derived from CD34+ progenitors and in the megakaryoblastic cell line UT7.
MATERIALS AND METHODS: Expression of Bcl-xL was analyzed in CD41+ cells cultured in
the presence of thrombopoietin and in UT7 cells treated with phorbol diester by Western …
