Is thrombopoietin interleukin 6?
N Williams - Experimental hematology, 1991 - europepmc.org
N Williams
Experimental hematology, 1991•europepmc.orgRecent data concerning to ability of interleukin 6 (IL-6) to stimulate platelet production have
raised the possibility that platelet production is not specifically regulated by a unique
feedback mechanism, but is part of a network encompassing several hemopoietic growth
factors. Hypotheses are presented about the nature of thrombopoietin, its relationship to
known growth factors, especially IL-6, and the specificity of a thrombopoietic response
following change in the circulating platelet mass.
raised the possibility that platelet production is not specifically regulated by a unique
feedback mechanism, but is part of a network encompassing several hemopoietic growth
factors. Hypotheses are presented about the nature of thrombopoietin, its relationship to
known growth factors, especially IL-6, and the specificity of a thrombopoietic response
following change in the circulating platelet mass.
Recent data concerning to ability of interleukin 6 (IL-6) to stimulate platelet production have raised the possibility that platelet production is not specifically regulated by a unique feedback mechanism, but is part of a network encompassing several hemopoietic growth factors. Hypotheses are presented about the nature of thrombopoietin, its relationship to known growth factors, especially IL-6, and the specificity of a thrombopoietic response following change in the circulating platelet mass.
europepmc.org
