[CITATION][C] Demonstration and some properties of human thrombopoietin in thrombocythaemic sera

E Kelemen, I Cserháti, B Tanos - Acta haematologica, 1958 - karger.com
E Kelemen, I Cserháti, B Tanos
Acta haematologica, 1958karger.com
Results Fig. 1 summarizes our results. In the cases where thrombocythaemic serum was
administered the elevation of the platelet count ranged from 50,000 to 250,000. 0.01 or 0.05
ml. of the thrombocythaemic sera were equally active, and an 81% increase of circulating
thrombocytes followed the administration of an amount of serum as small as 0.005 ml. in
saline. The activity did not increase with the elevation of the injected amount. The induced
thrombocytosis generally lasted up to 48-72 hours (fig. 1, IV.-V.).
Results
Fig. 1 summarizes our results. In the cases where thrombocythaemic serum was administered the elevation of the platelet count ranged from 50,000 to 250,000. 0.01 or 0.05 ml. of the thrombocythaemic sera were equally active, and an 81% increase of circulating thrombocytes followed the administration of an amount of serum as small as 0.005 ml. in saline. The activity did not increase with the elevation of the injected amount. The induced thrombocytosis generally lasted up to 48-72 hours (fig. 1, IV.-V.).
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