Reduced coronary events in simvastatin-treated patients with coronary heart disease and diabetes or impaired fasting glucose levels: subgroup analyses in the …

SM Haffner, CM Alexander, TJ Cook… - Archives of Internal …, 1999 - jamanetwork.com
Background Patients with diabetes mellitus (DM) have a marked increase in coronary heart
disease (CHD) events relative to those without DM. In a previous report from the
Scandinavian Simvastatin Survival Study using a clinical case definition of DM (n= 202),
simvastatin-treated patients had significantly fewer CHD events compared with placebo-
treated control subjects. Objective To examine the effect of simvastatin therapy on CHD in
patients with DM and impaired fasting glucose levels. Methods Using the 1997 American …