Eosinophils within the healthy or inflamed human intestine produce substance P and vasoactive intestinal peptide
A Metwali, AM Blum, L Ferraris, JS Klein… - Journal of …, 1994 - Elsevier
The purpose of this study was to show if inflammatory cells within healthy or diseased
human intestinal mucosa produce some regulatory neuropeptides. First, inflammatory cells
were isolated from the intestinal lamina propria of 11 patients with ulcerative colitis or
Crohn's disease. Also collected were cells from anatomically normal intestine derived from
five patients requiring bowel resection for diseases not related to inflammatory bowel
disease. Extracts of these isolated cells contained authentic substance P (SP) and …
human intestinal mucosa produce some regulatory neuropeptides. First, inflammatory cells
were isolated from the intestinal lamina propria of 11 patients with ulcerative colitis or
Crohn's disease. Also collected were cells from anatomically normal intestine derived from
five patients requiring bowel resection for diseases not related to inflammatory bowel
disease. Extracts of these isolated cells contained authentic substance P (SP) and …