[HTML][HTML] Sp1-binding elements in the promoter of RAGE are essential for amphoterin-mediated gene expression in cultured neuroblastoma cells
J Li, X Qu, AM Schmidt - Journal of Biological Chemistry, 1998 - ASBMB
Receptor for AGE (RAGE) and the polypeptide amphoterin are highly expressed and co-
localized in neurons of the developing central nervous system of the rat. In vitro, the
interaction of amphoterin with neuronal RAGE induces neurite outgrowth. We tested the
hypothesis that interaction of amphoterin with neuronal cells enhances RAGE expression,
thereby providing a mechanism by which amphoterin-mediated regulation of RAGE might
contribute to promotion of neurite growth and spreading. Incubation of cultured …
localized in neurons of the developing central nervous system of the rat. In vitro, the
interaction of amphoterin with neuronal RAGE induces neurite outgrowth. We tested the
hypothesis that interaction of amphoterin with neuronal cells enhances RAGE expression,
thereby providing a mechanism by which amphoterin-mediated regulation of RAGE might
contribute to promotion of neurite growth and spreading. Incubation of cultured …
